Dermagen

Aloe vera + Betamethasone + Benzocaine + Centella Asiatica + Gentamicin + Miconazole

Benefits

• Antibiotic: Gentamicin.
• Anti-inflammatory: Betamethasone.
• Antiallergic: Betamethasone.
• Analgesic: Benzocaine.
• Antifungal: Miconazole.
• Antipruritic: Benzocaine + Centella Asiatica.
• Healing: Aloe Vera + Centella Asiatica.

Description:

Antibiotic, anti-inflammatory, antiallergic, analgesic, antifungal, antipruritic and healing for topical use.

Composition:

Each 100 g of cream contains:

Gentamicin	0,1 g
Betamethasone	0,1 g
Miconazole Nitrate	2 g
Benzocaine	1 g
Centella Asiatica	1 g
Aloe Vera	0,07 g
Excipients q.s.	100 g

Indications:

Inflammatory dermatopathies associated with bacterial, fungal or mixed infection. Dermatitis secondarily infected by fungi or bacteria. Bacterial or fungal infections that have a marked inflammatory action. All kinds of wounds. Burns.

Therapeutic Action:

Gentamicin: it is an aminoglycoside antibiotic with activity on sensitive strains of Streptococcus (group A beta-hemolytic, alpha-hemolytic), Staphylococcus aureus (coagulase-positive, coagulase-negative, and on some gram-negative strains) such as Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus vulgaris and Klebsiella pneumoniae.

Betamethasone: it is a corticosteroid that applied topically develops an anti-inflammatory, antiallergic, antipruritic and vasoconstrictive action. Its topical mechanism of action is not well known. There is evidence that suggests a correlation between its vasoconstrictor potency and its therapeutic efficacy in humans.

Miconazole: it is a synthetic imidazole derivative that is active on most pathogenic fungi and yeasts, as well as on some Gram positive cocci and bacilli. The activity is based on the inhibition of ergosterol synthesis in the cell membrane of the pathogenic microorganism. This results in the accumulation of precursors by interfering with the synthesis of triglycerides and fatty acids, and in an inhibitory effect of oxidative and perioxidative enzymes. Accumulation of ergosterol precursors and toxic peroxides results in cytolysis.

The clinical efficacy of miconazole has been demonstrated on: dermatophytes, Tricophitum sp and Microsporum sp, Candida sp, Aspergillus sp, dimorphic fungi, Cryptococcus neoformans, Pityrosporum sp and Torulopsis glabrata, as well as on certain gram positive bacteria such as Erysipelothrix insidiosa, Streptococcus pyogenes and Staphilococcus aureus.

Benzocaine: eliminates pain and itching, an essential condition for rapid healing, also avoiding self-mutilation by scratching the patient.

Centella Asiatica: healing, antiseptic, phlebotonic, vasoprotective, astringent and antipruritic. Regarding the healing action, it has been shown to stimulate cellular mitosis and promote collagen biosynthesis at the connective tissue level, a key protein in wound healing. It has been shown that in wounds treated with Centella Asiatica there is an increase in the overall content of DNA, proteins and collagen in the granulation tissue, an increase in the rate of epithelialization and an increase in the levels of fibronectin, a glycoprotein with functions of intercellular adhesive. It also inhibits the inflammatory process that could cause scarring hypertrophy. Regarding venotonic action, studies have been carried out that confirm it in both experimental animals and humans.

Aloe Vera: Healing: increases the synthesis of glycosaminoglycans and proteoglycans constituting the scar matrix that is formed in the phases prior to the formation of granulation tissue in the wound. It also has immunostimulatory, anti-inflammatory, antibacterial and hydrating activity.

Dosage and Administration:

Apply a thin layer of Dermagen until the affected area is completely covered two or three times a day, or as directed by the Veterinary. The frequency of application will be determined according to the severity of the condition. The duration of therapy should be determined based on the patient's response. You must previously clean the area to be treated.

Species:

Horses, Dogs and Cats.